Description

IDE_Insulin Degrading Enzyme Mouse Monoclonal Antibody(REK0126)

Cat. No.

REK0126

Immunogen

 synthetic peptide coupled to KLH.

Concentration

1ug/ul

Specificity

The IDE mouse monoclonal antibody can detect endogenous IDEproteins.

MW

N/A

Substrate/Buffer

Phosphate buffered saline (PBS) with containing 0.02% sodium azide. pH 7.2.

Application

WB 1:5000 

 (Optimal dilutions should be determined by the end user)

Notes

Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently. 

Storage

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

Purity

Immunogen affinity purified

Clonality

Monoclonal

Isotype

 IgG1

Alternative names

Abeta-degrading protease antibody, insulin protease antibody, insulinase antibody, insulysin antibody