Description

CA IX Carbonic Anhydrase IX Mouse Monoclonal Antibody(REK0145)

Cat. No.

REK0145

Immunogen

 synthetic peptide coupled to KLH.

Concentration

1ug/ul

Specificity

The CA IX/Carbonic Anhydrase IX mouse monoclonal antibody can detect endogenous CA IX/Carbonic Anhydrase IX proteins.

MW

N/A

Substrate/Buffer

Phosphate buffered saline (PBS) with containing 0.02% sodium azide. pH 7.2.

Application

WB 1:5000 

 (Optimal dilutions should be determined by the end user)

Notes

The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. CAIX is considered to be one of the best cellular biomarkers of hypoxia. Furthermore, recent studies examining the association between CAIX levels and various clinicopathological outcomes suggest that CAIX expression may also be a valuable prognostic indicator for overall survival. Antibodies against CAIX serve as excellent excellent biomarkers of hypoxic regions in many solid tumors.     

Storage

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

Purity

Immunogen affinity purified

Clonality

Monoclonal

Isotype

 IgG1

Alternative names

CA9 antibody, Carbonic anhydrase 9 antibody, Renal cell carcinoma associated antigen G250 antibody